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Origins of MLL cancer stem cells govern leukemic self-renewal mediated by -catenin and Hoxa9

ABSTRACT: From mice, strand-specific RNA-Seq of granulocyte-myeloid progenitors (GMP) and hematopoietic stem cells (HSC). Cancer stem cells (CSC) were created with MLL-ENL transfections using puromycin for both GMP and HSCs. Further knock-outs were created of -catenin (Ctnnb1) and Hoxa9.

INSTRUMENT(S): Illumina HiSeq 2000

ORGANISM(S): Mus musculus

SUBMITTER: Bernd Zeisig

PROVIDER: E-MTAB-3647 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress

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