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RNAseq of murine primary bone marrow cells transformed by an inducible Hoxa9-ER: time-course

ABSTRACT: Relative overexpression of HOXA9 is a key feature of aggressive AML (acute myeloid leukemia). Hoxa9 responsive genes were identified by nascent RNA sequencing (4-thio-uridine labeled RNA - sequencing) in samples of primary hematopoietic precursor cells from mice transformed by an tamoxifen inducible version of Hoxa9 (Hoxa9-ER). Samples were generated in the presence of active Hoxa9 (0h) and in a time series after Hoxa9 was inactivated at 8h, 16h, 24h, 48h, and 72h.

INSTRUMENT(S): Illumina HiSeq 2500

ORGANISM(S): Mus musculus

SUBMITTER: Robert Slany

PROVIDER: E-MTAB-7107 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress

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