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Docetaxel response prediction MEEBO

ABSTRACT: Using gene expression profiling of mammary tumors generated in a mouse model for BRCA1-associated breast cancer we have searched for markers that correlate with response to the anti-cancer drugs docetaxel or cisplatin. To validate the results, the analysis was done on 2 different platforms (39K Mouse Exonic Evidence Based Oligonucleotide (MEEBO), and 45K Illumina Sentrix mouse V6 single-channel bead arrays). Moreover, we analyzed mouse mammary tumors that had acquired docetaxel resistance on the MEEBO platform.

ORGANISM(S): Mus musculus

DISEASE(S): mammary tumor

SUBMITTER: Iris de Rink

PROVIDER: E-MTAB-415 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress

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