Unknown,Transcriptomics,Genomics,Proteomics

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ATAC-seq of Oesophageal Cell Lines


ABSTRACT: ATAC-seq in oesophageal cell lines, OE33 (OAC), FLO1 (OAC), HET1A (Normal)

INSTRUMENT(S): Illumina HiSeq 2500

ORGANISM(S): Homo sapiens

SUBMITTER: Andrew Sharrocks 

PROVIDER: E-MTAB-4209 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress

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Publications


New biological tools are required to understand the functional significance of genetic events revealed by whole genome sequencing (WGS) studies in oesophageal adenocarcinoma (OAC). The MFD-1 cell line was isolated from a 55-year-old male with OAC without recombinant-DNA transformation. Somatic genetic variations from MFD-1, tumour, normal oesophagus, and leucocytes were analysed with SNP6. WGS was performed in tumour and leucocytes. RNAseq was performed in MFD-1, and two classic OAC cell lines F  ...[more]

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