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ATAC-seq of Oesophageal Cell Lines

ABSTRACT: ATAC-seq in oesophageal cell lines, OE33 (OAC), FLO1 (OAC), HET1A (Normal)

INSTRUMENT(S): Illumina HiSeq 2500

ORGANISM(S): Homo sapiens

SUBMITTER: Andrew Sharrocks

PROVIDER: E-MTAB-4209 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress

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Authentication and characterisation of a new oesophageal adenocarcinoma cell line: MFD-1.

Garcia Edwin E Hayden Annette A Birts Charles C Britton Edward E Cowie Andrew A Pickard Karen K Mellone Massimiliano M Choh Clarisa C Derouet Mathieu M Duriez Patrick P Noble Fergus F White Michael J MJ Primrose John N JN Strefford Jonathan C JC Rose-Zerilli Matthew M Thomas Gareth J GJ Ang Yeng Y Sharrocks Andrew D AD Fitzgerald Rebecca C RC Underwood Timothy J TJ

Scientific reports 20160907

New biological tools are required to understand the functional significance of genetic events revealed by whole genome sequencing (WGS) studies in oesophageal adenocarcinoma (OAC). The MFD-1 cell line was isolated from a 55-year-old male with OAC without recombinant-DNA transformation. Somatic genetic variations from MFD-1, tumour, normal oesophagus, and leucocytes were analysed with SNP6. WGS was performed in tumour and leucocytes. RNAseq was performed in MFD-1, and two classic OAC cell lines F ...[more]

PMID: 27600491

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2023-08-31 | E-MTAB-12821 | biostudies-arrayexpress

ATAC-seq of wild-type, Pbx1/Pbx2 double-knockout and pMsgn1-mut EpiSCs differentiated in vitro to pre-somitic mesoderm in the first 48 hours of differentiation.

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