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38 Diffuse Large B-Cell lymphomas

ABSTRACT: Frozen biopsies collected at diagnosis from 38 DLBCLs were analyzed to find recurrent copy number events in this disease. Hybridizations were performed against matching DNA samples extracted from Peripheral Blood Mononuclear Cells (PBMC).

ORGANISM(S): Homo sapiens

SUBMITTER: Fabrice Jardin

PROVIDER: E-MTAB-4495 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress

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Application of the cghRA framework to the genomic characterization of Diffuse Large B-Cell Lymphoma.

Mareschal Sylvain S Ruminy Philippe P Alcantara Marion M Villenet Céline C Figeac Martin M Dubois Sydney S Bertrand Philippe P Bouzelfen Abdelilah A Viailly Pierre-Julien PJ Penther Dominique D Tilly Hervé H Bastard Christian C Jardin Fabrice F

Bioinformatics (Oxford, England) 20171001 19

<h4>Motivation</h4>Although sequencing-based technologies are becoming the new reference in genome analysis, comparative genomic hybridization arrays (aCGH) still constitute a simple and reliable approach for copy number analysis. The most powerful algorithms to analyze such data have been freely provided by the scientific community for many years, but combining them is a complex scripting task.<h4>Results</h4>The cghRA framework combines a user-friendly graphical interface and a powerful object ...[more]

PMID: 28481978

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