Unknown,Transcriptomics,Genomics,Proteomics

Dataset Information

MiRNA profiling of pre- and postoperative breast tumors

ABSTRACT: Gene expression studies on breast cancer have generally been performed on tissue obtained at the time of surgery. Overexpression of several genes may be a result of surgical trauma or preoperative manipulation, and may not reflect any biological impact of the disease. This study compares the expression profiles in preoperative tissue while tumor is still in its normal milieu to postoperative tissue from the same tumor obtained during surgery.

ORGANISM(S): Homo sapiens

SUBMITTER: Torben Lüders

PROVIDER: E-MTAB-469 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress

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Publications

Molecular profiles of pre- and postoperative breast cancer tumours reveal differentially expressed genes.

Riis Margit L H ML Lüders Torben T Markert Elke K EK Haakensen Vilde D VD Nesbakken Anne-Jorun AJ Kristensen Vessela N VN Bukholm Ida R K IR

ISRN oncology 20121126

Gene expression studies on breast cancer have generally been performed on tissue obtained at the time of surgery. In this study, we have compared the gene expression profiles in preoperative tissue (core needle biopsies) while tumor is still in its normal milieu to postoperative tissue from the same tumor obtained during surgery. Thirteen patients were included of which eleven had undergone sentinel node diagnosis procedure before operation. Microarray gene expression analysis was performed usin ...[more]

PMID: 23227362

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Dataset Information

MiRNA profiling of pre- and postoperative breast tumors

Publications

Molecular profiles of pre- and postoperative breast cancer tumours reveal differentially expressed genes.

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