Dataset Information
The transcriptional signature of human ovarian carcinoma macrophages is associated with extracellular matrix reorganization
Ontology highlight
ABSTRACT:
INSTRUMENT(S): Illumina HiSeq 1500
ORGANISM(S): Homo sapiens
SUBMITTER: Rolf Muller
PROVIDER: E-MTAB-4764 | biostudies-arrayexpress |
REPOSITORIES: biostudies-arrayexpress
Publications
The transcriptional signature of human ovarian carcinoma macrophages is associated with extracellular matrix reorganization.
Oncotarget 20161101 46
Macrophages occur as resident cells of fetal origin or as infiltrating blood monocyte-derived cells. Despite the critical role of tumor-associated macrophages (TAMs) in tumor progression, the contribution of these developmentally and functionally distinct macrophage subsets and their alteration by the tumor microenvironment are poorly understood. We have addressed this question by comparing TAMs from human ovarian carcinoma ascites, resident peritoneal macrophages (pMPHs) and monocyte-derived ma ...[more]
