Colony stimulating factor (CSF1) treatment of kidneys that have undergone ischemia reperfusion injury
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ABSTRACT: Mice were subjected to renal artery clamps to induce ischemia/reperfusion injury to the kidney. 3 days post surgery mice were injected with CSF1 or PBS daily for a further 3 days. Mice were sacrificed 5 and 7 days post surgey and the kidney was removed and homogenised into single cell suspensions. Cells were selected on their expression of CD45, CD11b markers and the lack of CD11c. These cells were then subjected to microarray analyses to determine the global gene expresssion profiles of mice with and without treatment.
ORGANISM(S): Mus Musculus
SUBMITTER: Sharon Ricardo
PROVIDER: E-MTAB-557 | biostudies-arrayexpress |
REPOSITORIES: biostudies-arrayexpress
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