Ontology highlight
ABSTRACT:
ORGANISM(S): Homo sapiens
SUBMITTER: Jane Synnergren
PROVIDER: E-MTAB-6045 | biostudies-arrayexpress |
REPOSITORIES: biostudies-arrayexpress
Holmgren Gustav G Synnergren Jane J Bogestål Yalda Y Améen Caroline C Åkesson Karolina K Holmgren Sandra S Lindahl Anders A Sartipy Peter P
Toxicology 20141218
Doxorubicin is a chemotherapeutic agent indicated for the treatment of a variety of cancer types, including leukaemia, lymphomas, and many solid tumours. The use of doxorubicin is, however, associated with severe cardiotoxicity, often resulting in early discontinuation of the treatment. Importantly, the toxic symptoms can occur several years after the termination of the doxorubicin administration. In this study, the toxic effects of doxorubicin exposure have been investigated in cardiomyocytes d ...[more]