Dataset Information
Transcription profiling by high throughput sequencing of Dirofilaria immitis adult male and female worms
Ontology highlight
ABSTRACT:
ORGANISM(S): Dirofilaria immitis
SUBMITTER: Mark Blaxter
PROVIDER: E-MTAB-714 | biostudies-arrayexpress |
REPOSITORIES: biostudies-arrayexpress
Publications
The genome of the heartworm, Dirofilaria immitis, reveals drug and vaccine targets.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 20120813 11
The heartworm Dirofilaria immitis is an important parasite of dogs. Transmitted by mosquitoes in warmer climatic zones, it is spreading across southern Europe and the Americas at an alarming pace. There is no vaccine, and chemotherapy is prone to complications. To learn more about this parasite, we have sequenced the genomes of D. immitis and its endosymbiont Wolbachia. We predict 10,179 protein coding genes in the 84.2 Mb of the nuclear genome, and 823 genes in the 0.9-Mb Wolbachia genome. The ...[more]
