Daylight regulation of cardiac gene expression in wild type and Per2 deficient mice.
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ABSTRACT: Daylight is fundamental to human health and protects from myocardial ischemia in a PER2 dependent manner. Using a whole genome array from daylight exposed wildtype or Per2-/- mice, we investigated light elicited pathways.Mice were exposed to intense light (10,000 LUX, Lightbox simulating day light, Uplift Technologies DL930 Day-Light 10,000 Lux SAD, full spectrum) for 7 days and compared to mice maintained at room light [200 LUX]. Mice were housed in a 14/10-h light-dark cycle to synchronize (entrain) the circadian clock of mice to the ambient light-dark cycle.
ORGANISM(S): Mus musculus
SUBMITTER: Tobias Eckle
PROVIDER: E-MTAB-7196 | biostudies-arrayexpress |
REPOSITORIES: biostudies-arrayexpress
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