Ontology highlight
ABSTRACT:
INSTRUMENT(S): Illumina HiSeq 4000
ORGANISM(S): Pseudomonas aeruginosa
SUBMITTER: Andrea Sass
PROVIDER: E-MTAB-7331 | biostudies-arrayexpress |
REPOSITORIES: biostudies-arrayexpress
Vandeplassche Eva E Sass Andrea A Lemarcq Astrid A Dandekar Ajai A AA Coenye Tom T Crabbé Aurélie A
Scientific reports 20190906 1
In cystic fibrosis (CF) airways, the opportunistic pathogen Pseudomonas aeruginosa evolves from an acute to a chronic infection phenotype. Yet, the in vivo factors influencing the evolutionary trajectory of P. aeruginosa are poorly understood. This study aimed at understanding the role of the CF lung microbiome in P. aeruginosa evolution. Therefore, we investigated the in vitro biofilm evolution of an early CF P. aeruginosa isolate, AA2, in the presence or absence of a synthetic CF lung microbio ...[more]