Genes differentially expressed in MLL-AF9-transduced versus HOXA9/MEIS1-transduced LSK cells
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ABSTRACT: HOXA9 and MEIS1 are essential downstream effectors of the MLL-AF9 oncoprotein during leukaemia induction. Leukaemia derived from MLL-AF9-transduced LSK cells has a more aggressive phenotype than that derived from HOXA9/MEIS1-transduced LSK cells. To determine differential gene expression that contributes to increased aggressiveness in MLL-AF9-induced leukaemia, microarray was performed on LSK cells transduced with MLL-AF9 versus HOXA/MEIS1 oncogenes.
ORGANISM(S): Mus musculus
SUBMITTER: Jenny Wang
PROVIDER: E-MTAB-7355 | biostudies-arrayexpress |
REPOSITORIES: biostudies-arrayexpress
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