Ontology highlight
ABSTRACT:
INSTRUMENT(S): Illumina HiSeq 4000
ORGANISM(S): Plasmodium falciparum 3D7
SUBMITTER: Tim Gilberger
PROVIDER: E-MTAB-7731 | biostudies-arrayexpress |
REPOSITORIES: biostudies-arrayexpress
Wichers J Stephan JS Scholz Judith A M JAM Strauss Jan J Witt Susanne S Lill Andrés A Ehnold Laura-Isabell LI Neupert Niklas N Liffner Benjamin B Lühken Renke R Petter Michaela M Lorenzen Stephan S Wilson Danny W DW Löw Christian C Lavazec Catherine C Bruchhaus Iris I Tannich Egbert E Gilberger Tim W TW Bachmann Anna A
mBio 20190730 4
During its intraerythrocytic development, the malaria parasite <i>Plasmodium falciparum</i> exposes variant surface antigens (VSAs) on infected erythrocytes to establish and maintain an infection. One family of small VSAs is the polymorphic STEVOR proteins, which are marked for export to the host cell surface through their PEXEL signal peptide. Interestingly, some STEVORs have also been reported to localize to the parasite plasma membrane and apical organelles, pointing toward a putative functio ...[more]