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The role of DNA repair endonuclease XPF in transcription

ABSTRACT: In this experiment we want to explore and compare the bindind of XPF in normal MEFs, in tRA treated MEFs and in UV radiated MEFs

INSTRUMENT(S): Illumina HiSeq 4000

ORGANISM(S): Mus musculus

SUBMITTER: George Garinis

PROVIDER: E-MTAB-8154 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress

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XAB2 binds genome-wide on putative DNA elements (e.g. enhancers, promoters) that are known to regulate gene expression

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The role of DNA repair endonuclease XPF in transcription

Project description:The role of DNA repair endonuclease XPF in transcription

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RNA-seq of mouse DNA repair endonuclease XPF knock out versus wild type and versus trans retinoic acid (tRA) treated wild type

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P300-mediated adaptive conversion of glioma stem cells to vascular-like cells in response to therapeutic stress promotes tumor recurrence [RNA-seq_sorted GEC GPC]

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Gene expression induced in HEK293 by treatment with the differentiating agents all-trans retinoic acid (tRA) and N6,2'-O-dibutyryl-cAMP (cAMP)

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Expression data from Sotos syndrome patients and controls

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Multiple DNA repair pathways collectively protect against DNA damage-induced replicative aging.

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