Ontology highlight
ABSTRACT:
ORGANISM(S): Homo sapiens
DISEASE(S): tumour
SUBMITTER: Michal Kolar
PROVIDER: E-MTAB-850 | biostudies-arrayexpress |
REPOSITORIES: biostudies-arrayexpress
International journal of cancer 20120409 11
Tumor stroma is an active part influencing the biological properties of malignancies via molecular cross-talk. Cancer-associated fibroblasts play a significant role in this interaction. These cells frequently express smooth muscle actin and can be classified as myofibroblasts. The adhesion/growth-regulatory lectin galectin-1 is an effector for their generation. In our study, we set the presence of smooth muscle actin-positive cancer-associated fibroblasts in relation to this endogenous lectin an ...[more]