Effects of increased intracellular calcium and overnutrition on pancreatic beta cell transcriptome
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ABSTRACT: To determine the individual and combined effects of excitotoxicity and overnutrition on beta-cell gene expression, we analyzed the impact of a high fat diet (HFD) on wild type C57Bl/6J and Abcc8 knockout mice of different sexes. We collected 31 bulk RNA-Seq datasets that originated from FACS-purified pancreatic beta-cells that differed by genotype, diet, and sex.
INSTRUMENT(S): Illumina NovaSeq 6000
ORGANISM(S): Mus musculus
SUBMITTER: Mark Magnuson
PROVIDER: E-MTAB-8643 | biostudies-arrayexpress |
REPOSITORIES: biostudies-arrayexpress
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