Ontology highlight
ABSTRACT:
INSTRUMENT(S): NextSeq 500
ORGANISM(S): Homo sapiens
SUBMITTER: Xiaohui Zhao
PROVIDER: E-MTAB-9284 | biostudies-arrayexpress |
REPOSITORIES: biostudies-arrayexpress
Cindrova-Davies Tereza T Zhao Xiaohui X Elder Kay K Jones Carolyn J P CJP Moffett Ashley A Burton Graham J GJ Turco Margherita Y MY
Communications biology 20210617 1
Assessment of the endometrium often necessitates a biopsy, which currently involves an invasive, transcervical procedure. Here, we present an alternative technique based on deriving organoids from menstrual flow. We demonstrate that organoids can be derived from gland fragments recovered from menstrual flow. To confirm they faithfully reflect the in vivo state we compared organoids derived from paired scratch biopsies and ensuing menstrual flow from patients undergoing in vitro fertilisation (IV ...[more]