Unknown,Transcriptomics,Genomics,Proteomics

Dataset Information

Evaluation of methylmercury on neural development in Embryonic Stem Cell Differentiation Cultures

ABSTRACT: Effects of methylmercury on stem cell neural development at four differernt culture time points

ORGANISM(S): Mus Musculus

SUBMITTER: Jeroen Pennings

PROVIDER: E-TABM-1108 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress

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Publications

Time-response evaluation by transcriptomics of methylmercury effects on neural differentiation of murine embryonic stem cells.

Theunissen Peter T PT Pennings Jeroen L A JL Robinson Joshua F JF Claessen Sandra M H SM Kleinjans Jos C S JC Piersma Aldert H AH

Toxicological sciences : an official journal of the Society of Toxicology 20110525 2

Current globally harmonized Organisation for Economic Co-operation and Development (OECD) animal test guidelines for developmental toxicity require high numbers of experimental animals. To reduce animal use in this field, alternative developmental toxicity assays are highly desirable. We previously developed a dynamic in vitro model for screening effects of possible neurodevelopmental toxicants, using neural cell differentiation of pluripotent murine embryonic stem cells. To further mechanistica ...[more]

PMID: 21613230

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Dataset Information

Evaluation of methylmercury on neural development in Embryonic Stem Cell Differentiation Cultures

Publications

Time-response evaluation by transcriptomics of methylmercury effects on neural differentiation of murine embryonic stem cells.

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