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Transcription profiling of wild type and transcriptional regulator mutant strains of Sinorhizobium meliloti

ABSTRACT: Comparative transcriptome analysis between a Sinorhizobium meliloti wild-type strain and different mutants deficient for transcriptional regulators.

ORGANISM(S): Sinorhizobium meliloti

SUBMITTER: Christine Bobik 

PROVIDER: E-TABM-122 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress

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Publications

FixJ: a major regulator of the oxygen limitation response and late symbiotic functions of Sinorhizobium meliloti.

Bobik Christine C   Meilhoc Eliane E   Batut Jacques J  

Journal of bacteriology 20060701 13

Sinorhizobium meliloti exists either in a free-living state in the soil or in symbiosis within legume nodules, where the bacteria differentiate into nitrogen-fixing bacteroids. Expression of genes involved in nitrogen fixation and associated respiration is governed by two intermediate regulators, NifA and FixK, respectively, which are controlled by a two-component regulatory system FixLJ in response to low-oxygen conditions. In order to identify the FixLJ regulon, gene expression profiles were d  ...[more]

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