Ontology highlight
ABSTRACT:
ORGANISM(S): Mus musculus
SUBMITTER: Riny Janssen
PROVIDER: E-TABM-221 | biostudies-arrayexpress |
REPOSITORIES: biostudies-arrayexpress
Janssen Riny R Pennings Jeroen J Hodemaekers Hennie H Buisman Annemarie A van Oosten Marijke M de Rond Lia L Oztürk Kemal K Dormans Jan J Kimman Tjeerd T Hoebee Barbara B
Journal of virology 20070321 11
Respiratory syncytial virus (RSV) is a common cause of severe lower respiratory tract infection in children. Severe RSV disease is related to an inappropriate immune response to RSV resulting in enhanced lung pathology which is influenced by host genetic factors. To gain insight into the early pathways of the pathogenesis of and immune response to RSV infection, we determined the transcription profiles of lungs and lymph nodes on days 1 and 3 after infection of mice. Primary RSV infection result ...[more]