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Metabolomics,Unknown,Transcriptomics,Genomics,Proteomics

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Transcription profiling of mouse embryoid body differentation in a time series

ABSTRACT: Expression profiling of a 16 day mouse embryoid body (EB) differentiation time course.

ORGANISM(S): Mus musculus

SUBMITTER: Marcel Dinger

PROVIDER: E-TABM-433 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress

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Long noncoding RNAs in mouse embryonic stem cell pluripotency and differentiation.

Dinger Marcel E ME Amaral Paulo P PP Mercer Tim R TR Pang Ken C KC Bruce Stephen J SJ Gardiner Brooke B BB Askarian-Amiri Marjan E ME Ru Kelin K Soldà Giulia G Simons Cas C Sunkin Susan M SM Crowe Mark L ML Grimmond Sean M SM Perkins Andrew C AC Mattick John S JS

Genome research 20080618 9

The transcriptional networks that regulate embryonic stem (ES) cell pluripotency and lineage specification are the subject of considerable attention. To date such studies have focused almost exclusively on protein-coding transcripts. However, recent transcriptome analyses show that the mammalian genome contains thousands of long noncoding RNAs (ncRNAs), many of which appear to be expressed in a developmentally regulated manner. The functions of these remain untested. To identify ncRNAs involved ...[more]

PMID: 18562676

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