Ontology highlight
ABSTRACT:
ORGANISM(S): Drosophila melanogaster
SUBMITTER: Ariel Paulson
PROVIDER: E-TABM-527 | biostudies-arrayexpress |
REPOSITORIES: biostudies-arrayexpress
Mastushita-Sakai Tomoko T White-Grindley Erica E Samuelson Jessica J Seidel Chris C Si Kausik K
Proceedings of the National Academy of Sciences of the United States of America 20100614 26
In the study of long-term memory, how memory persists is a fundamental and unresolved question. What are the molecular components of the long-lasting memory trace? Previous studies in Aplysia and Drosophila have found that a neuronal variant of a RNA-binding protein with a self-perpetuating prion-like property, cytoplasmic polyadenylation element binding protein, is required for the persistence of long-term synaptic facilitation in the snail and long-term memory in the fly. In this study, we hav ...[more]