Dataset Information
Transcription profiling of Baseline gene expression in circulating peripheral blood mononuclear cells isolated from 18 apparently healthy volunteers (10 females and 8 males)
Ontology highlight
ABSTRACT:
?Aged between 20 and 45 years of age;
?A non-smoker (or an ex-smoker);
?Not pregnant or been pregnant in the last 12 months
?Not diagnosed with any long-term medical condition;
?Or have not (in the previous 4 months) donated blood, received any inoculations and are not taking regular prescribed medicine (including HRT and oral contraception)
Prior to inclusion in this study volunteers were screened for general health and had a blood sample taken for routine screening of Hb content etc. Only those volunteers who were in good general health were allowed to participate in the study.
The age of all volunteers has been reported here as being 20-45 years in order to preserve the anonymity of the data, and so that the individuals involved may not be able to track down their own specific data. Please contact us if the details of volunteers' ages are required.
ORGANISM(S): Homo sapiens
SUBMITTER: John Eady
PROVIDER: E-TABM-7 | biostudies-arrayexpress |
REPOSITORIES: biostudies-arrayexpress
Publications
Variation in gene expression profiles of peripheral blood mononuclear cells from healthy volunteers.
Physiological genomics 20050712 3
The normal degree of intra- and interindividual variation in gene transcription profiles of healthy human tissues has not been extensively investigated. In the study described here, microarrays were employed to analyze gene transcription in peripheral blood mononuclear cells prepared from serial blood samples that had been obtained, at weekly intervals, from apparently healthy human volunteers. Transcript levels for the majority of genes examined were found to be remarkably consistent within sam ...[more]
