Ontology highlight
ABSTRACT:
ORGANISM(S): Homo sapiens
DISEASE(S): extranodal NK/T-Cell Lymphoma derived cell line
SUBMITTER: Aurelien de Reynies
PROVIDER: E-TABM-791 | biostudies-arrayexpress |
REPOSITORIES: biostudies-arrayexpress
Blood 20091130 6
Biopsies and cell lines of natural killer/T-cell lymphoma, nasal type (NKTCL) were subject to combined gene expression profiling and array-based comparative genomic hybridization analyses. Compared with peripheral T-cell lymphoma, not otherwise specified, NKTCL had greater transcript levels for NK-cell and cytotoxic molecules, especially granzyme H. Compared with normal NKcells, tumors were closer to activated than resting cells and overexpressed several genes related to vascular biology, Epstei ...[more]