Ontology highlight
ABSTRACT:
ORGANISM(S): Mus musculus
SUBMITTER: Susan Anderson
PROVIDER: E-TABM-865 | biostudies-arrayexpress |
REPOSITORIES: biostudies-arrayexpress
Noyes Harry A HA Agaba Morris M Anderson Susan S Archibald Alan L AL Brass Andy A Gibson John J Hall Laurence L Hulme Helen H Oh Sung Jong SJ Kemp Stephen S
BMC genomics 20100607
<h4>Background</h4>Differences in gene expression may be caused by nearby DNA polymorphisms (cis regulation) or by interactions of gene control regions with polymorphic transcription factors (trans regulation). Trans acting loci are much harder to detect than cis acting loci and their effects are much more sensitive to genetic background.<h4>Results</h4>To quantify cis and trans regulation we correlated haplotype data with gene expression in two inbred mouse strains and two derived congenic line ...[more]