Metabolomics,Unknown,Transcriptomics,Genomics,Proteomics

Dataset Information

0

Chromatin immunoprecipitation genome wide map of nucleosome acetylation and methylation in Yeast

ABSTRACT: Genomes are packaged into nucleosomes whose position and modification state can profoundly influence regulation of gene expression. We have established new ChIP-based high-resolution genome-wide maps of histone acetylation and methylation that take into account changes in nucleosome occupancy at actively transcribed genes. These maps provide a more accurate picture of nucleosome occupancy and the nature of modifications associated with transcriptional activity in this eukaryotic genome. We describe the combination of modifications that occur at the average transcribed gene.

INSTRUMENT(S): vortex

ORGANISM(S): Saccharomyces cerevisiae

SUBMITTER: Elizabeth Herbolsheimer 

PROVIDER: E-WMIT-3 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress

Json Xml
altmetric image

Publications

Eukaryotic genomes are packaged into nucleosomes whose position and chemical modification state can profoundly influence regulation of gene expression. We profiled nucleosome modifications across the yeast genome using chromatin immunoprecipitation coupled with DNA microarrays to produce high-resolution genome-wide maps of histone acetylation and methylation. These maps take into account changes in nucleosome occupancy at actively transcribed genes and, in doing so, revise previous assessments o  ...[more]

Similar Datasets

Transcriptomics Chromatin immunoprecipitation genome wide binding site identification in yeast
2013-01-30 | E-WMIT-1 | biostudies-arrayexpress
Transcriptomics Chromatin immunoprecipitation genome wide occupancy of 4 different chromatin regulating complexes encoded in yeast
2005-11-03 | E-WMIT-2 | biostudies-arrayexpress
Transcriptomics Chromatin immunoprecipitation genome wide location analysis of yeast transcriptional regulators under multiple growth conditions
2004-09-02 | E-WMIT-10 | biostudies-arrayexpress
Transcriptomics Chromatin immunoprecipitation of activated yeast signal transduction protein kinases
2006-07-28 | E-TABM-98 | biostudies-arrayexpress
Transcriptomics Transcription profiling of synchronized Sulfolobus acidocaldarius populations as they progress through the cell cycle
2007-12-08 | E-MEXP-936 | biostudies-arrayexpress
Transcriptomics Transcription profiling of hyperthermophilic crenarchaea Sulfolobus solfataricus and Sulfolobus acidocaldarius to UV irradiation
2007-11-21 | E-MEXP-1252 | biostudies-arrayexpress
Transcriptomics Transcription profiling of heptatocytes from mice given a high-copper diet
2007-06-01 | E-MEXP-745 | biostudies-arrayexpress
no omics defined Transcription profiling of human hepatocytes in response to copper overload at nine time points
2007-06-01 | E-MEXP-753 | biostudies-arrayexpress
Transcriptomics Transcription profiling of homozygous Commd1 null mouse embryos to elucidate the underlying mechanism leading to embryonic lethality
2006-09-01 | E-MEXP-832 | biostudies-arrayexpress
Transcriptomics Transcription profiling of matching human primary head and neck squamous cell carcinomas and cervical lymph node metastases.
2006-10-23 | E-TABM-114 | biostudies-arrayexpress