At Long Last: Short, All-Oral Regimens for Multidrug-Resistant Tuberculosis in the United States.
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SUBMITTER: Sinha P
PROVIDER: S-EPMC10135426 | biostudies-literature | 2023 Apr
REPOSITORIES: biostudies-literature
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At Long Last: Short, All-Oral Regimens for Multidrug-Resistant Tuberculosis in the United States.
Sinha Pranay P Jacobson Karen R KR Horsburgh C Robert CR Acuña-Villaorduña Carlos C
Open forum infectious diseases 20230403 4
Multidrug-resistant tuberculosis (MDR-TB) has historically required longer treatment regimens that were associated with higher unfavorable outcomes and side effects rates compared with drug susceptible TB (DS-TB). During the last decade, several studies conducted mostly in high-incidence settings have shown that MDR-TB can be successfully treated using all-oral shorter regimens of 6- to 9-month duration. In this article, we review the evolution of MDR-TB treatment from the early long regimens wi ...[more]
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