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Risk factors for postpartum maternal mortality and hospital readmission in low- and middle-income countries: a systematic review.


ABSTRACT:

Background

In low- and middle-income countries, approximately two thirds of maternal deaths occur in the postpartum period. Yet, care for women beyond 24 h after discharge is limited. The objective of this systematic review is to summarize current evidence on socio-demographic and clinical risk factors for (1) postpartum mortality and (2) postpartum hospital readmission.

Methods

A combination of keywords and subject headings (i.e. MeSH terms) for postpartum maternal mortality or readmission were searched. Articles published up to January 9, 2021 were identified in MEDLINE, EMBASE, and CINAHL databases, without language restrictions. Studies reporting socio-demographic or clinical risk factors for postpartum mortality or readmission within six weeks of delivery among women who delivered a livebirth in a low- or middle-income country were included. Data were extracted independently by two reviewers based on study characteristics, population, and outcomes. Included studies were assessed for quality and risk of bias using the Downs and Black checklist for ratings of randomized and non-randomized studies.

Results

Of 8783 abstracts screened, seven studies were included (total N = 387,786). Risk factors for postpartum mortality included Caesarean mode of delivery, nulliparity, low or very low birthweight, and shock upon admission. Risk factors for postpartum readmission included Caesarean mode of delivery, HIV positive serostatus, and abnormal body temperature.

Conclusions

Few studies reported individual socio-demographic or clinical risk factors for mortality or readmission after delivery in low- and middle-income countries; only Caesarean delivery was consistently reported. Further research is needed to identify factors that put women at greatest risk of post-discharge complications and mortality. Understanding post-discharge risk would facilitate targeted postpartum care and reduce adverse outcomes in women after delivery.

Trial registration

PROSPERO registration number: CRD42018103955.

SUBMITTER: Symonds NE 

PROVIDER: S-EPMC10148415 | biostudies-literature | 2023 Apr

REPOSITORIES: biostudies-literature

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Publications

Risk factors for postpartum maternal mortality and hospital readmission in low- and middle-income countries: a systematic review.

Symonds Nicola E NE   Vidler Marianne M   Wiens Matthew O MO   Omar Shazmeen S   English L Lacey LL   Ukah U Vivian UV   Ansermino J Mark JM   Ngonzi Joseph J   Bebell Lisa M LM   Hwang Bella B   Christoffersen-Deb Astrid A   Kissoon Niranjan N   Payne Beth A BA  

BMC pregnancy and childbirth 20230429 1


<h4>Background</h4>In low- and middle-income countries, approximately two thirds of maternal deaths occur in the postpartum period. Yet, care for women beyond 24 h after discharge is limited. The objective of this systematic review is to summarize current evidence on socio-demographic and clinical risk factors for (1) postpartum mortality and (2) postpartum hospital readmission.<h4>Methods</h4>A combination of keywords and subject headings (i.e. MeSH terms) for postpartum maternal mortality or r  ...[more]

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