Ontology highlight
ABSTRACT:
SUBMITTER: McBride TM
PROVIDER: S-EPMC10212523 | biostudies-literature | 2023 Apr
REPOSITORIES: biostudies-literature
McBride Tess M TM Cameron Shaharn C SC Fineran Peter C PC Fagerlund Robert D RD
The Biochemical journal 20230401 7
Prokaryotes have adaptive defence mechanisms that protect them from mobile genetic elements and viral infection. One defence mechanism is called CRISPR-Cas (clustered regularly interspaced short palindromic repeats and CRISPR-associated proteins). There are six different types of CRISPR-Cas systems and multiple subtypes that vary in composition and mode of action. Type I and III CRISPR-Cas systems utilise multi-protein complexes, which differ in structure, nucleic acid binding and cleaving prefe ...[more]