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Tn5706, a transposon-like element from Pasteurella multocida mediating tetracycline resistance.

ABSTRACT: The 4,378-bp putative tetracycline resistance transposon Tn5706 of Pasteurella multocida consists of an internal tet(H)-tetR resistance gene region which is flanked by almost identical insertion elements, IS1596 and IS1597. Two reading frames for proteins of 70 and 228 amino acids were detected in each of these insertion sequence elements. The 228-amino-acid protein revealed homology to transposase proteins of gram-positive bacteria.

SUBMITTER: Kehrenberg C

PROVIDER: S-EPMC105878 | biostudies-literature | 1998 Aug

REPOSITORIES: biostudies-literature

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Tn5706, a transposon-like element from Pasteurella multocida mediating tetracycline resistance.

Kehrenberg C C Werckenthin C C Schwarz S S

Antimicrobial agents and chemotherapy 19980801 8

The 4,378-bp putative tetracycline resistance transposon Tn5706 of Pasteurella multocida consists of an internal tet(H)-tetR resistance gene region which is flanked by almost identical insertion elements, IS1596 and IS1597. Two reading frames for proteins of 70 and 228 amino acids were detected in each of these insertion sequence elements. The 228-amino-acid protein revealed homology to transposase proteins of gram-positive bacteria. ...[more]

PMID: 9687418

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