Ontology highlight
ABSTRACT:
SUBMITTER: Heusch G
PROVIDER: S-EPMC10590874 | biostudies-literature | 2023 Nov
REPOSITORIES: biostudies-literature
Heusch Gerd G Andreadou Ioanna I Bell Robert R Bertero Edoardo E Botker Hans-Erik HE Davidson Sean M SM Downey James J Eaton Philip P Ferdinandy Peter P Gersh Bernard J BJ Giacca Mauro M Hausenloy Derek J DJ Ibanez Borja B Krieg Thomas T Maack Christoph C Schulz Rainer R Sellke Frank F Shah Ajay M AM Thiele Holger H Yellon Derek M DM Di Lisa Fabio F
Redox biology 20231006
The present review summarizes the beneficial and detrimental roles of reactive oxygen species in myocardial ischemia/reperfusion injury and cardioprotection. In the first part, the continued need for cardioprotection beyond that by rapid reperfusion of acute myocardial infarction is emphasized. Then, pathomechanisms of myocardial ischemia/reperfusion to the myocardium and the coronary circulation and the different modes of cell death in myocardial infarction are characterized. Different mechanic ...[more]