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Cloning, characterization, and expression analysis of hepcidin gene from red sea bream (Chrysophrys major).


ABSTRACT: A cDNA encoding hepcidin was isolated from a library of cDNA from spleen of red sea bream (Chrysophrys major) by expressed sequence tag analysis. The expression of the hepcidin mRNA in various tissues was examined. Challenge of red sea bream with Escherichia coli DH5alpha elevated hepcidin mRNA levels in spleen, gill, liver, and intestine.

SUBMITTER: Chen SL 

PROVIDER: S-EPMC1068609 | biostudies-literature | 2005 Apr

REPOSITORIES: biostudies-literature

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Cloning, characterization, and expression analysis of hepcidin gene from red sea bream (Chrysophrys major).

Chen Song-Lin SL   Xu Mei-Yu MY   Ji Xiang-Shan XS   Yu Guo-Cai GC   Liu Yang Y  

Antimicrobial agents and chemotherapy 20050401 4


A cDNA encoding hepcidin was isolated from a library of cDNA from spleen of red sea bream (Chrysophrys major) by expressed sequence tag analysis. The expression of the hepcidin mRNA in various tissues was examined. Challenge of red sea bream with Escherichia coli DH5alpha elevated hepcidin mRNA levels in spleen, gill, liver, and intestine. ...[more]

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