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Pollen self-elimination CRISPR-Cas genome editing prevents transgenic pollen dispersal in maize.

ABSTRACT: This study reports the development of a programmed pollen self-elimination CRISPR-Cas (PSEC) system in which the pollen is infertile when PSEC is present in haploid pollen. PSEC can be inherited through the female gametophyte and retains genome editing activity in vivo across generations. This system could greatly alleviate serious concerns about the widespread diffusion of genetically modified (GM) elements into natural and agricultural environments via outcrossing.

SUBMITTER: Wang H

PROVIDER: S-EPMC10721481 | biostudies-literature | 2023 Nov

REPOSITORIES: biostudies-literature

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Pollen self-elimination CRISPR-Cas genome editing prevents transgenic pollen dispersal in maize.

Wang Honglin H Qi Xiantao X Zhu Jinjie J Liu Changlin C Fan Hongwei H Zhang Xuecai X Li Xinhai X Yang Qin Q Xie Chuanxiao C

Plant communications 20230610 6

This study reports the development of a programmed pollen self-elimination CRISPR-Cas (PSEC) system in which the pollen is infertile when PSEC is present in haploid pollen. PSEC can be inherited through the female gametophyte and retains genome editing activity in vivo across generations. This system could greatly alleviate serious concerns about the widespread diffusion of genetically modified (GM) elements into natural and agricultural environments via outcrossing. ...[more]

PMID: 37301980

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