Ontology highlight
ABSTRACT:
SUBMITTER: Lee RMQ
PROVIDER: S-EPMC10913850 | biostudies-literature | 2023
REPOSITORIES: biostudies-literature
Lee Rachel Min Qi RMQ Koh Tong-Wey TW
Oxford open neuroscience 20230309
α-Synuclein is a pleiotropic protein underlying a group of progressive neurodegenerative diseases, including Parkinson's disease and dementia with Lewy bodies. Together, these are known as synucleinopathies. Like all neurological diseases, understanding of disease mechanisms is hampered by the lack of access to biopsy tissues, precluding a real-time view of disease progression in the human body. This has driven researchers to devise various experimental models ranging from yeast to flies to huma ...[more]