Small RNA-modulated anaerobic respiration allows bacteria to survive under antibiotic stress conditions.
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ABSTRACT:
SUBMITTER: Kim D
PROVIDER: S-EPMC10993149 | biostudies-literature | 2024
REPOSITORIES: biostudies-literature
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Small RNA-modulated anaerobic respiration allows bacteria to survive under antibiotic stress conditions.
Kim Dajeong D Bhat Abhayprasad A Kim Seon-Kyu SK Lee Soohyun S Ryu Choong-Min CM
Frontiers in cellular and infection microbiology 20240313
Despite extensive knowledge of antibiotic-targeted bacterial cell death, deeper understanding of antibiotic tolerance mechanisms is necessary to combat multi-drug resistance in the global healthcare settings. Regulatory RNAs in bacteria control important cellular processes such as cell division, cellular respiration, metabolism, and virulence. Here, we investigated how exposing <i>Escherichia coli</i> to the moderately effective first-generation antibiotic cephalothin alters transcriptional and ...[more]
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