Ontology highlight
ABSTRACT:
SUBMITTER: Ataman M
PROVIDER: S-EPMC11316767 | biostudies-literature | 2024 Aug
REPOSITORIES: biostudies-literature
Ataman Meric M Mittal Nitish N Tintignac Lionel L Schmidt Alexander A Ham Daniel J DJ González Asier A Ruegg Markus A MA Zavolan Mihaela M
Communications biology 20240810 1
Calorie restriction (CR) and treatment with rapamycin (RM), an inhibitor of the mTORC1 growth-promoting signaling pathway, are known to slow aging and promote health from worms to humans. At the transcriptome and proteome levels, long-term CR and RM treatments have partially overlapping effects, while their impact on protein phosphorylation within cellular signaling pathways have not been compared. Here we measured the phosphoproteomes of soleus, tibialis anterior, triceps brachii and gastrocnem ...[more]