Ontology highlight
ABSTRACT:
SUBMITTER: Dehinwal R
PROVIDER: S-EPMC11322160 | biostudies-literature | 2024 Aug
REPOSITORIES: biostudies-literature
Dehinwal Ruchika R Gopinath Tata T Smith Richard D RD Ernst Robert K RK Schifferli Dieter M DM Waldor Matthew K MK Marassi Francesca M FM
Nature communications 20240813 1
Outer membrane vesicles (OMVs) produced by Gram-negative bacteria have key roles in cell envelope homeostasis, secretion, interbacterial communication, and pathogenesis. The facultative intracellular pathogen Salmonella Typhimurium increases OMV production inside the acidic vacuoles of host cells by changing expression of its outer membrane proteins and modifying the composition of lipid A. However, the molecular mechanisms that translate pH changes into OMV production are not completely underst ...[more]