Ontology highlight
ABSTRACT:
SUBMITTER: Bruhn H
PROVIDER: S-EPMC1175101 | biostudies-literature | 2005 Jul
REPOSITORIES: biostudies-literature
The Biochemical journal 20050701 Pt 2
SAPLIPs (saposin-like proteins) are a diverse family of lipid-interacting proteins that have various and only partly understood, but nevertheless essential, cellular functions. Their existence is conserved in phylogenetically most distant organisms, such as primitive protozoa and mammals. Owing to their remarkable sequence variability, a common mechanism for their actions is not known. Some shared principles beyond their diversity have become evident by analysis of known three-dimensional struct ...[more]