Ontology highlight
ABSTRACT:
SUBMITTER: Bellais S
PROVIDER: S-EPMC127090 | biostudies-literature | 2002 Apr
REPOSITORIES: biostudies-literature
Bellais Samuel S Naas Thierry T Nordmann Patrice P
Antimicrobial agents and chemotherapy 20020401 4
Antibiotic susceptibility testing by disk diffusion of a Chryseobacterium gleum isolate, strain CIP 103039, showed a typical synergy image between clavulanic acid and expanded-spectrum cephalosporins. Shotgun cloning gave a recombinant plasmid in Escherichia coli that produced a beta-lactamase, CGA-1, with a pI value of 8.9 that conferred resistance to most penicillins (except ureidopenicillins) and narrow-spectrum cephalosporins and an intermediate susceptibility to expanded-spectrum cephalospo ...[more]