Simultaneous expression of different variant-specific surface proteins in single Giardia lamblia trophozoites during encystation.
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ABSTRACT:
SUBMITTER: Carranza PG
PROVIDER: S-EPMC128263 | biostudies-literature | 2002 Sep
REPOSITORIES: biostudies-literature
Publications
Simultaneous expression of different variant-specific surface proteins in single Giardia lamblia trophozoites during encystation.
Carranza Pedro G PG Feltes Gisela G Ropolo Andrea A Quintana Silvia M C SM Touz María C MC Luján Hugo D HD
Infection and immunity 20020901 9
A novel variant-specific surface protein (VSP) from Giardia was identified using the monoclonal antibody 9B10, raised against purified cyst walls. VSP9B10B is preferentially induced during encystation and expressed simultaneously with other VSPs on the surface of encysting trophozoites. These results support the hypothesis that encystation and antigenic variation are processes that are mechanistically related. ...[more]
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