Ontology highlight
ABSTRACT:
SUBMITTER: Casas I
PROVIDER: S-EPMC1317187 | biostudies-literature | 2005 Dec
REPOSITORIES: biostudies-literature
Casas I I Avellon A A Mosquera M M Jabado O O Echevarria J E JE Campos R H RH Rewers M M Perez-Breña P P Lipkin W I WI Palacios G G
Journal of clinical microbiology 20051201 12
Here we present a system for adenovirus detection and genotyping based on PCR amplification and phylogenetic analysis of a conserved hexon gene fragment. The system was validated using 157 sequences (86 previously typed and 71 clinical samples) and correctly identified species and serotype in 100% and 84% of sequences, respectively. Known associations between specific serotypes and clinical syndromes are verified. Possible new associations are described to allow further independent testing. ...[more]