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First detection of metallo-beta-lactamase VIM-2 in Pseudomonas aeruginosa isolates from Colombia.


ABSTRACT: Carbapenem resistance rates in Pseudomonas aeruginosa isolates in Colombia, as in many South American countries, are high for reasons that remain unclear. From our nationwide network, we describe the first detection of the metallo-beta-lactamase VIM-2 in clinical isolates of P. aeruginosa from multiple cities within Colombia. Metallo-beta-lactamases were not detected in the two centers with the highest imipenem resistance rates. Clonality was noted in five of the eight centers with strains meeting the criteria for molecular typing. The high carbapenem resistance in P. aeruginosa in Colombia may be attributable to a combination of factors, including the presence of metallo-beta-lactamases and nosocomial transmission.

SUBMITTER: Villegas MV 

PROVIDER: S-EPMC1346812 | biostudies-literature | 2006 Jan

REPOSITORIES: biostudies-literature

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First detection of metallo-beta-lactamase VIM-2 in Pseudomonas aeruginosa isolates from Colombia.

Villegas Maria Virginia MV   Lolans Karen K   del Rosario Olivera Maria M   Suarez Carlos José CJ   Correa Adriana A   Queenan Anne Marie AM   Quinn John P JP  

Antimicrobial agents and chemotherapy 20060101 1


Carbapenem resistance rates in Pseudomonas aeruginosa isolates in Colombia, as in many South American countries, are high for reasons that remain unclear. From our nationwide network, we describe the first detection of the metallo-beta-lactamase VIM-2 in clinical isolates of P. aeruginosa from multiple cities within Colombia. Metallo-beta-lactamases were not detected in the two centers with the highest imipenem resistance rates. Clonality was noted in five of the eight centers with strains meeti  ...[more]

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