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Identification of human herpesvirus 6 latency-associated transcripts.


ABSTRACT: Four kinds of latency-associated transcripts of human herpesvirus 6 were identified which were detected only in latently infected cells. Although they were oriented in the same direction as the immediate-early 1 and 2 (IE1/IE2) genes and shared their protein-coding region with IE1/IE2, their transcription start sites and exon(s) were latency associated.

SUBMITTER: Kondo K 

PROVIDER: S-EPMC136062 | biostudies-literature | 2002 Apr

REPOSITORIES: biostudies-literature

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Identification of human herpesvirus 6 latency-associated transcripts.

Kondo Kazuhiro K   Shimada Kazuya K   Sashihara Junji J   Tanaka-Taya Keiko K   Yamanishi Koichi K  

Journal of virology 20020401 8


Four kinds of latency-associated transcripts of human herpesvirus 6 were identified which were detected only in latently infected cells. Although they were oriented in the same direction as the immediate-early 1 and 2 (IE1/IE2) genes and shared their protein-coding region with IE1/IE2, their transcription start sites and exon(s) were latency associated. ...[more]

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