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Asian genotypes of JC virus in Japanese-Americans suggest familial transmission.

ABSTRACT: To examine the mode of JC virus (JCV) transmission, we collected urine samples from second- and third-generation Japanese-Americans in Los Angeles, Calif., whose parents and grandparents were all Japanese. From the urine samples of these Japanese-Americans, we mainly detected two subtypes (CY and MY) of JCV that are predominantly found among native Japanese. This finding provides support for the hypothesis that JCV is transmitted mainly within the family through long-term cohabitation.

SUBMITTER: Suzuki M

PROVIDER: S-EPMC136522 | biostudies-literature | 2002 Oct

REPOSITORIES: biostudies-literature

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Asian genotypes of JC virus in Japanese-Americans suggest familial transmission.

Suzuki Makoto M Zheng Huai-Ying HY Takasaka Tomokazu T Sugimoto Chie C Kitamura Tadaichi T Beutler Ernest E Yogo Yoshiaki Y

Journal of virology 20021001 19

To examine the mode of JC virus (JCV) transmission, we collected urine samples from second- and third-generation Japanese-Americans in Los Angeles, Calif., whose parents and grandparents were all Japanese. From the urine samples of these Japanese-Americans, we mainly detected two subtypes (CY and MY) of JCV that are predominantly found among native Japanese. This finding provides support for the hypothesis that JCV is transmitted mainly within the family through long-term cohabitation. ...[more]

PMID: 12208989

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