Ontology highlight
ABSTRACT:
SUBMITTER: Jones SW
PROVIDER: S-EPMC1367334 | biostudies-literature | 2006 Mar
REPOSITORIES: biostudies-literature
Jones Stephen W SW Friel David D DD
Biophysical journal 20060113 5
Neurotransmitters, hormones, or dyes may be released from vesicles via a fusion pore, rather than by full fusion of the vesicle with the plasma membrane. If the lifetime of the fusion pore is comparable to the time required for the substance to exit the vesicle, only a fraction of the total vesicle content may be released during a single pore opening. Assuming 1), fusion pore lifetimes are exponentially distributed (tauP), as expected for simple single channel openings, and 2), vesicle contents ...[more]