Ontology highlight
ABSTRACT:
SUBMITTER: Barrera FN
PROVIDER: S-EPMC1386033 | biostudies-literature | 2006 Feb
REPOSITORIES: biostudies-literature
Barrera Francisco N FN Hurtado-Gómez Estefanía E Lidón-Moya María C MC Neira José L JL
The Biochemical journal 20060201 Pt 1
The capsid protein, CA, of HIV-1 forms a capsid that surrounds the viral genome. However, recent studies have shown that an important proportion of the CA molecule does not form part of this capsid, and its location and function are still unknown. In the present work we show, by using fluorescence, differential scanning calorimetry and Fourier-transform infrared spectroscopy, that the C-terminal region of CA, CA-C, is able to bind lipid vesicles in vitro in a peripheral fashion. CA-C had a great ...[more]