Ontology highlight
ABSTRACT:
SUBMITTER: Suefuji K
PROVIDER: S-EPMC139220 | biostudies-literature | 2002 Dec
REPOSITORIES: biostudies-literature
Suefuji Kyoko K Valluzzi Regina R RayChaudhuri Debabrata D
Proceedings of the National Academy of Sciences of the United States of America 20021213 26
Accurate positioning of the division septum at the equator of Escherichia coli cells requires a rapid oscillation of MinD ATPase between the polar halves of the cell membrane, together with the division inhibitor MinC, under MinE control. The mechanism underlying MinD oscillation remains poorly understood. Here, we demonstrate that purified MinD assembles into protein filaments in the presence of ATP. Incubation with phospholipid vesicles further stimulates MinD polymerization. Addition of purif ...[more]