Ontology highlight
ABSTRACT:
SUBMITTER: Wu W
PROVIDER: S-EPMC3077903 | biostudies-literature | 2011 Mar
REPOSITORIES: biostudies-literature
Wu Wei W Park Kyung-Tae KT Holyoak Todd T Lutkenhaus Joe J
Molecular microbiology 20110124 6
The three Min proteins spatially regulate Z ring positioning in Escherichia coli and are dynamically associated with the membrane. MinD binds to vesicles in the presence of ATP and can recruit MinC or MinE. Biochemical and genetic evidence indicate the binding sites for these two proteins on MinD overlap. Here we solved the structure of a hydrolytic-deficient mutant of MinD truncated for the C-terminal amphipathic helix involved in binding to the membrane. The structure solved in the presence of ...[more]