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Intermolecular rhodium-catalyzed [2+2+2] carbocyclization reactions of 1,6-enynes with symmetrical and unsymmetrical alkynes.

ABSTRACT: The crossed intermolecular rhodium-catalyzed [2+2+2] carbocyclization of carbon and heteroatom tethered 1,6-enynes can be accomplished with symmetrical and unsymmetrical alkynes, to afford the corresponding bicyclohexadienes in an efficient and highly selective manner.

SUBMITTER: Evans PA

PROVIDER: S-EPMC1475740 | biostudies-literature | 2005 Aug

REPOSITORIES: biostudies-literature

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Intermolecular rhodium-catalyzed [2+2+2] carbocyclization reactions of 1,6-enynes with symmetrical and unsymmetrical alkynes.

Evans P Andrew PA Sawyer James R JR Lai Kwong Wah KW Huffman John C JC

Chemical communications (Cambridge, England) 20050707 31

The crossed intermolecular rhodium-catalyzed [2+2+2] carbocyclization of carbon and heteroatom tethered 1,6-enynes can be accomplished with symmetrical and unsymmetrical alkynes, to afford the corresponding bicyclohexadienes in an efficient and highly selective manner. ...[more]

PMID: 16075089

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